Regulation of X-Chromosome Inactivation in Development in Mice and Humans
نویسندگان
چکیده
منابع مشابه
Regulation of X-chromosome inactivation in development in mice and humans.
Dosage compensation for X-linked genes in mammals is accomplished by inactivating one of the two X chromosomes in females. X-chromosome inactivation (XCI) occurs during development, coupled with cell differentiation. In somatic cells, XCI is random, whereas in extraembryonic tissues, XCI is imprinted in that the paternally inherited X chromosome is preferentially inactivated. Inactivation is in...
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ژورنال
عنوان ژورنال: Microbiology and Molecular Biology Reviews
سال: 1998
ISSN: 1092-2172,1098-5557
DOI: 10.1128/mmbr.62.2.362-378.1998